RRC ID 28672
Author Hata M, Suzuki M, Matsumoto M, Takahashi M, Sato K, Ibe S, Sakae K.
Title Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b.
Journal Antimicrob. Agents Chemother.
Abstract A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.
Volume 49(2)
Pages 801-3
Published 2005-2
DOI 10.1128/AAC.49.2.801-803.2005
PII 49/2/801
PMID 15673773
PMC PMC547361
MeSH Amino Acid Sequence Anti-Bacterial Agents / pharmacology* Cloning, Molecular Drug Resistance, Bacterial Escherichia coli / drug effects Escherichia coli / genetics Microbial Sensitivity Tests Molecular Sequence Data Mutation / genetics Plasmids / genetics* Quinolones / pharmacology* Reverse Transcriptase Polymerase Chain Reaction Shigella flexneri / drug effects* Shigella flexneri / genetics*
IF 4.256
Times Cited 197
WOS Category PHARMACOLOGY & PHARMACY MICROBIOLOGY
Resource
DNA material pBC-H2.6 (RDB05463) pBC-H8.4 (RDB05464)