| RRC ID |
29116
|
| 著者 |
Ueno K, Hui CC, Fukuta M, Suzuki Y.
|
| タイトル |
Molecular analysis of the deletion mutants in the E homeotic complex of the silkworm Bombyx mori.
|
| ジャーナル |
Development
|
| Abstract |
The E loci in Bombyx mori are expected to contain a homeotic gene complex specifying the identities of the larval abdominal segments. However, the molecular structure of this complex remains to be determined. We have started to analyze the structural changes in the E complex mutations. We used three newly isolated Bombyx homeobox genes as probes. These genes are probably homologues of the Ultrabithorax (Ubx), abdominal-A (abd-A) and Abdominal-B (Abd-B) in the Drosophila bithorax complex, because the amino-acid sequences of the homeobox regions in these Bombyx genes are almost identical to those of Drosophila genes. We found that the Bombyx Ubx and abd-A genes are deleted in the EN chromosome, and the Bombyx abd-A gene is deleted in the ECa chromosome. From these results, we conclude that the Bombyx E complex consists of the Ubx, abd-A and possibly Abd-B genes, which may play similar roles to their homologues in the Drosophila bithorax complex.
|
| 巻・号 |
114(3)
|
| ページ |
555-63
|
| 公開日 |
1992-3-1
|
| DOI |
10.1242/dev.114.3.555
|
| 解説 |
BmUbxはショウジョウバエのホメオティック遺伝子であるabd-Aのカイコホモログである。ENを持ったf12系統の第6染色体では、BmUbxとBmabd-Aが欠失している。
Bmabd-Aはショウジョウバエのホメオティック遺伝子であるabd-Aのカイコホモログである。Ecaを持ったf21系統の第6染色体では、Bmabd-A遺伝子が欠失している。
|
| PMID |
1352236
|
| MeSH |
Amino Acid Sequence
Animals
Base Sequence
Blotting, Southern
Bombyx / genetics*
Chromosome Deletion*
Cloning, Molecular
DNA / isolation & purification
Genes, Homeobox / genetics*
Molecular Sequence Data
Mutation / genetics*
Phenotype
Polymerase Chain Reaction
Sequence Homology, Nucleic Acid
|
| IF |
5.611
|
| 引用数 |
59
|
|
WOS 分野
|
DEVELOPMENTAL BIOLOGY
|
| リソース情報 |
| カイコ |
f12
f21 |
