Reference - Detail
| RRC ID | 29927 |
|---|---|
| Author | Lloyd RG, Low B, Godson GN, Birge EA. |
| Title | Isolation and characterization of an Escherichia coli K-12 mutant with a temperature-sensitive recA- phenotype. |
| Journal | J Bacteriol |
| Abstract |
A mutation that causes a temperature-sensitive RecA(-) phenotype was identified in a derivative of a PolA(-) strain that failed to grow at high temperature. The mutant allele (recA200) was shown to be linked to cysC, conferred a sharply temperature-sensitive, ultraviolet-sensitive Rec(-) phenotype in the range 35 to 42 C, and in crosses failed to show complementation at 42 C with Hfr's that transferred recA(-). Double mutants that carried both recA200 and polA were examined for ability to grow and synthesize DNA at restrictive temperatures. |
| Volume | 120(1) |
| Pages | 407-15 |
| Published | 1974-10-1 |
| DOI | 10.1128/jb.120.1.407-415.1974 |
| PMID | 4607624 |
| PMC | PMC245777 |
| MeSH | Alleles Cell Survival Chromosome Mapping Conjugation, Genetic DNA Nucleotidyltransferases / biosynthesis DNA, Bacterial / biosynthesis Escherichia coli* / enzymology Escherichia coli* / growth & development Escherichia coli* / isolation & purification Escherichia coli* / metabolism Escherichia coli* / radiation effects Genes Genetic Complementation Test Genetic Linkage Mutagens Mutation* Nitrosoguanidines Phenotype Radiation Effects Recombination, Genetic* Temperature Thymidine / metabolism Transduction, Genetic Tritium Ultraviolet Rays |
| IF | 3.006 |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Resource | |
| Prokaryotes E. coli | ME5401 ME7101 |