RRC ID 30003
Author Pittard J, Wallace BJ.
Title Distribution and function of genes concerned with aromatic biosynthesis in Escherichia coli.
Journal J Bacteriol
Abstract Pittard, James (School of Microbiology, University of Melbourne, Victoria, Australia), and B. J. Wallace. Distribution and function of genes concerned with aromatic biosynthesis in Escherichia coli. J. Bacteriol. 91:1494-1508. 1966.-A number of mutant strains of Escherichia coli K-12, which are blocked in the biosynthesis of the aromatic amino acids, were examined biochemically to determine their particular enzymatic deficiencies. The mutations carried by these strains were mapped by use of the methods of conjugation and transduction. Structural genes for five of the enzymes of the common pathway leading to chorismate and for the two enzymes converting chorismate to phenylpyruvate and p-hydroxyphenylpyruvate, respectively, were identified. Unlike the genes of the tryptophan operon most of these genes are distributed over widely separated regions of the chromosome.
Volume 91(4)
Pages 1494-508
Published 1966-4-1
DOI 10.1128/JB.91.4.1494-1508.1966
PMID 5326114
PMC PMC316068
MeSH Amino Acids / biosynthesis* Chromatography Chromosome Mapping Escherichia coli / enzymology* Escherichia coli / metabolism* Genes* Hydro-Lyases In Vitro Techniques Kinetics Mutation Phenylpyruvic Acids / metabolism* Shikimic Acid / metabolism
IF 3.234
Resource
Prokaryotes E. coli ME5352 JE5588