Reference - Detail
| RRC ID | 30008 |
|---|---|
| Author | Wallace BJ, Pittard J. |
| Title | Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli. |
| Journal | J Bacteriol |
| Abstract |
Mutant strains of Escherichia coli K-12 were isolated possessing mutations which affected the tyrosine-inhibitable 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase, the phenylalanine-inhibitable DAHP synthetase, or the tryptophan-repressible DAHP synthetase. The mutations causing the loss of each of these activities have been mapped and are widely separated from each other on the E. coli chromosome. Chromatography on diethylaminoethyl cellulose columns allowed the recognition of four peaks of activity. |
| Volume | 93(1) |
| Pages | 237-44 |
| Published | 1967-1-1 |
| DOI | 10.1128/jb.93.1.237-244.1967 |
| PMID | 5335890 |
| PMC | PMC314994 |
| MeSH | Amino Acids / biosynthesis* Chromatography Chromosome Mapping* Enzyme Repression Escherichia coli / enzymology* Escherichia coli / isolation & purification* Isoenzymes / analysis* Ligases / analysis* Mutation Phenylalanine / pharmacology Tryptophan / pharmacology Tyrosine / pharmacology |
| IF | 3.006 |
| Resource | |
| Prokaryotes E. coli | JE5588 ME5324 ME8637 |