| RRC ID |
30063
|
| 著者 |
Loewen PC.
|
| タイトル |
Isolation of catalase-deficient Escherichia coli mutants and genetic mapping of katE, a locus that affects catalase activity.
|
| ジャーナル |
J Bacteriol
|
| Abstract |
A number of catalase-deficient mutants of Escherichia coli which exhibit no assayable catalase activity were isolated. The only physiological difference between the catalase mutants and their parents was a 50- to 60-fold greater sensitivity to killing by hydrogen peroxide. For comparison, mutations in the xthA and recA genes of the same strains increased the sensitivity of the mutants to hydrogen peroxide by seven- and fivefold, respectively, showing that catalase was the primary defense against hydrogen peroxide. One class of mutants named katE was localized between pfkB and xthA at 37.8 min on the E. coli genome. A second class of catalase mutants was found which did not map in this region.
|
| 巻・号 |
157(2)
|
| ページ |
622-6
|
| 公開日 |
1984-2-1
|
| DOI |
10.1128/jb.157.2.622-626.1984
|
| PMID |
6319370
|
| PMC |
PMC215291
|
| MeSH |
Catalase / genetics*
DNA Restriction Enzymes
Escherichia coli / enzymology
Escherichia coli / genetics*
Genes*
Genes, Bacterial*
Genotype
Mutation*
Transduction, Genetic
|
| IF |
3.006
|
| 引用数 |
148
|
|
WOS 分野
|
MICROBIOLOGY
|
| リソース情報 |
| 原核生物(大腸菌) |
ME8299 |
