RRC ID 30360
著者 Kamikawa R, Yabuki A, Nakayama T, Ishida K, Hashimoto T, Inagaki Y.
タイトル Cercozoa comprises both EF-1α-containing and EFL-containing members.
ジャーナル Eur J Protistol
Abstract Elongation factor 1α (EF-1α) and elongation factor-like protein (EFL) are considered to be functionally equivalent proteins involved in peptide synthesis. Eukaryotes can be fundamentally divided into 'EF-1α-containing' and 'EFL-containing' types. Recently, EF-1α and EFL genes have been surveyed across the diversity of eukaryotes to explore the origin and evolution of EFL genes. Although the phylum Cercozoa is a diverse group, gene data for either EFL or EF-1α are absent from all cercozoans except chlorarachniophytes which were previously defined as EFL-containing members. Our survey revealed that two members of the cercozoan subphylum Filosa (Thaumatomastix sp. and strain YPF610) are EFL-containing members. Importantly, we identified EF-1α genes from two members of Filosa (Paracercomonas marina and Paulinella chromatophora) and a member of the other subphylum Endomyxa (Filoreta japonica). All cercozoan EFL homologues could not be recovered as a monophyletic group in maximum-likelihood and Bayesian analyses, suggesting that lateral gene transfer was involved in the EFL evolution in this protist assemblage. In contrast, EF-1α analysis successfully recovered a monophyly of three homologues sampled from the two cercozoan subphyla. Based on the results, we postulate that cercozoan EF-1α genes have been vertically inherited, and the current EFL-containing species may have secondarily lost their EF-1α genes.
巻・号 47(1)
ページ 24-8
公開日 2011-1-1
DOI 10.1016/j.ejop.2010.08.002
PII S0932-4739(10)00051-9
PMID 21071191
MeSH Cercozoa / genetics* Evolution, Molecular Gene Deletion Gene Transfer, Horizontal Peptide Elongation Factors / genetics* Phylogeny* Protozoan Proteins / genetics* Sequence Homology, Amino Acid
IF 2.395
引用数 10
WOS 分野 MICROBIOLOGY
リソース情報
藻類 NIES-2378