Reference - Detail
RRC ID | 3138 |
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Author | Araki A, Tsuda M, Kubota T, Mikami Y, Fromont J, Kobayashi J. |
Title | Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge Agelas species. |
Journal | Org Lett |
Abstract |
A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring. |
Volume | 9(12) |
Pages | 2369-71 |
Published | 2007-6-7 |
DOI | 10.1021/ol0707867 |
PMID | 17503838 |
MeSH | Agelas / chemistry* Alkaloids / chemistry* Alkaloids / isolation & purification Alkaloids / pharmacology Animals Cryptococcus neoformans / drug effects Magnetic Resonance Spectroscopy / methods Microbial Sensitivity Tests Models, Molecular Molecular Structure Pyrroles / chemistry* Pyrroles / isolation & purification Pyrroles / pharmacology Sensitivity and Specificity Species Specificity Staphylococcus aureus / drug effects Structure-Activity Relationship |
IF | 6.091 |
Times Cited | 36 |
WOS Category | CHEMISTRY, ORGANIC |
Resource | |
Pathogenic microorganisms | NA |