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  • Search Condition : Filter (MeSH = Pyrroles / pharmacology)
Species Resource Title
Human and Animal Cells ST2(RCB0224) Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone.
Prokaryotes B. subtilis Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria.
Human and Animal Cells HuCCT1(RCB1960) , YSCCC(RCB1549) Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells.
Human and Animal Cells PC-9(RCB4455) , A549 Effect of platinum‑based chemotherapy on the expression of natural killer group 2 member D ligands, programmed cell death‑1 ligand 1 and HLA class I in non‑small cell lung cancer.
Human and Animal Cells K562 Pharmacological inhibition of JAK3 enhances the antitumor activity of imatinib in human chronic myeloid leukemia.
Prokaryotes E. coli JW5503, JD17464 Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.
Mice RBRC02370 Microglia increases the proliferation of retinal precursor cells during postnatal development.
Human and Animal Cells MH7A(RCB1512) Kinase inhibitors of the IGF-1R as a potential therapeutic agent for rheumatoid arthritis.
Human and Animal Cells LC-2/ad(RCB0440) EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells.
DNA material CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362) , CSII-EF-MCS-IRES2-hKO1 (RDB07915) , CSII-EF-MCS-IRES2-Venus (RDB04384) , CS-RfA-ETBsd (RDB07917) , pENTR4-H1tetOx1 (RDB07916). Genetic regulation of the RUNX transcription factor family has antitumor effects.
Pathogenic microorganisms NA Nagelamides Q and R, novel dimeric bromopyrrole alkaloids from sponges Agelas sp.
C.elegans tm4189 , tm4127 , tm3933 , tm4845 , tm4391 , tm4516 CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Human and Animal Cells THP-1(RCB1189) Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice: potential roles of interleukin-6 and endothelin.
Human and Animal Cells ATDC5(RCB0565) ATP oscillations mediate inductive action of FGF and Shh signalling on prechondrogenic condensation.
Human and Animal Cells P19CL6 Eosinophil cationic protein enhances cardiomyocyte differentiation of P19CL6 embryonal carcinoma cells by stimulating the FGF receptor signaling pathway.
Human and Animal Cells Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.
Human and Animal Cells PC-12(RCB0009) Stimulation of catecholamine biosynthesis via the PKC pathway by prolactin-releasing peptide in PC12 rat pheochromocytoma cells.
Human and Animal Cells PC-12(RCB0009) BMP-2 augments FGF-induced differentiation of PC12 cells through upregulation of FGF receptor-1 expression.
Human and Animal Cells Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line.
Pathogenic microorganisms NA Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge Agelas species.