RRC ID |
31863
|
著者 |
Fukushima K, Arai T, Mori Y, Tsuboi M, Suzuki M.
|
タイトル |
Studies on peptide antibiotics, leucinostatins. I. Separation, physico-chemical properties and biological activities of leucinostatins A and B.
|
ジャーナル |
J Antibiot (Tokyo)
|
Abstract |
Leucinostatin, a peptide antibiotic, was separated by silica gel and alumina column chromatography into two related components designated as leucinostatin A hydrochloride (C61H111-N11O13.HCl) and leucinostatin B hydrochloride (C61H109N11O13.HCl). Physico-chemical as well as biological properties of the two separated components were analyzed. These properties pointed to closely resembling chemical structures.
|
巻・号 |
36(12)
|
ページ |
1606-12
|
公開日 |
1983-12-1
|
DOI |
10.7164/antibiotics.36.1606
|
PMID |
6662804
|
MeSH |
Animals
Anti-Bacterial Agents* / isolation & purification*
Anti-Bacterial Agents* / toxicity
Antimicrobial Cationic Peptides
Chromatography, High Pressure Liquid / methods
Chromatography, Thin Layer / methods
Drug Evaluation, Preclinical
Fungi / drug effects
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Mitochondria, Liver / drug effects
Mitochondria, Liver / metabolism
Oxygen Consumption / drug effects
Peptides / isolation & purification
Peptides / toxicity
Rats
Spectrophotometry, Infrared
Structure-Activity Relationship
|
IF |
2.668
|
引用数 |
39
|
WOS 分野
|
PHARMACOLOGY & PHARMACY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
MICROBIOLOGY
IMMUNOLOGY
|
リソース情報 |
病原微生物 |
IFM 40005
IFM 40006
IFM 40007
IFM 40009 |