RRC ID 32198
著者 Tachibana T, Matsuyama T, Ito M, Mitsuyama M.
タイトル Sporothrix schenckii thermo-intolerant mutants losing fatal visceral infectivity but retaining high cutaneous infectivity.
ジャーナル Med Mycol
Abstract Four mutants of the Sporothrix schenckii lung isolate IFM 41598 were isolated by their inability to form colonies on a Sabouraud glucose agar plate incubated at 37 degrees C for 4 days. In contrast to the parent IFM 41598, these thermo-intolerant mutants were all defective in producing fatal visceral infections in mice, even though they retained infectivity in footpad tissues with a small fungal inoculum (approximately equals 10 cfu).
巻・号 39(3)
ページ 295-8
公開日 2001-6-1
DOI 10.1080/mmy.39.3.295.298
PMID 11446534
MeSH Animals Dermatomycoses / microbiology* Dermatomycoses / physiopathology Foot / microbiology Genes, Fungal Humans Lung Diseases, Fungal / microbiology Male Mice Mice, Inbred BALB C Mutation* Nitrosoguanidines Sporothrix / genetics* Sporothrix / pathogenicity* Sporotrichosis / microbiology* Sporotrichosis / physiopathology Temperature Virulence
IF 2.822
引用数 6
WOS 分野 VETERINARY SCIENCES MYCOLOGY INFECTIOUS DISEASES
リソース情報
病原微生物 IFM 5906 IFM 41598 IFM 46010 IFM 46011 IFM 46365