論文 - 詳細
RRC ID | 32198 |
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著者 | Tachibana T, Matsuyama T, Ito M, Mitsuyama M. |
タイトル | Sporothrix schenckii thermo-intolerant mutants losing fatal visceral infectivity but retaining high cutaneous infectivity. |
ジャーナル | Med Mycol |
Abstract |
Four mutants of the Sporothrix schenckii lung isolate IFM 41598 were isolated by their inability to form colonies on a Sabouraud glucose agar plate incubated at 37 degrees C for 4 days. In contrast to the parent IFM 41598, these thermo-intolerant mutants were all defective in producing fatal visceral infections in mice, even though they retained infectivity in footpad tissues with a small fungal inoculum (approximately equals 10 cfu). |
巻・号 | 39(3) |
ページ | 295-8 |
公開日 | 2001-6-1 |
DOI | 10.1080/mmy.39.3.295.298 |
PMID | 11446534 |
MeSH | Animals Dermatomycoses / microbiology* Dermatomycoses / physiopathology Foot / microbiology Genes, Fungal Humans Lung Diseases, Fungal / microbiology Male Mice Mice, Inbred BALB C Mutation* Nitrosoguanidines Sporothrix / genetics* Sporothrix / pathogenicity* Sporotrichosis / microbiology* Sporotrichosis / physiopathology Temperature Virulence |
IF | 2.822 |
引用数 | 6 |
WOS 分野 | VETERINARY SCIENCES MYCOLOGY INFECTIOUS DISEASES |
リソース情報 | |
病原微生物 | IFM 5906 IFM 41598 IFM 46010 IFM 46011 IFM 46365 |