RRC ID 3307
Author Eydallin G, Viale AM, Morán-Zorzano MT, Muñoz FJ, Montero M, Baroja-Fernández E, Pozueta-Romero J.
Title Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12.
Journal FEBS Lett.
Abstract A systematic and comprehensive gene-disrupted mutant collection of E. coli K-12 was used to identify genes whose deletions affect glycogen accumulation. Of the 3985 non-essential gene mutants of the collection, 35 displayed a glycogen-excess phenotype, whereas 30 displayed either glycogen-less or glycogen-deficient phenotypes. The genes whose deletions affect glycogen accumulation were classified into various functional categories, including energy production, envelope composition and integrity, protein translation and stability, transport of inorganic ions and nucleotides, and metabolism of carbohydrates and amino acids. The overall data indicate that glycogen metabolism is highly interconnected with a wide variety of cellular processes in E. coli.
Volume 581(16)
Pages 2947-53
Published 2007-6-26
DOI 10.1016/j.febslet.2007.05.044
PII S0014-5793(07)00571-6
PMID 17543954
MeSH Amino Acids / metabolism Bacterial Outer Membrane Proteins / metabolism Carbohydrate Metabolism / genetics Energy Metabolism / genetics Escherichia coli K12 / genetics* Escherichia coli K12 / metabolism* Gene Deletion Genes, Bacterial Genome, Bacterial* Genomics / methods Glycogen / metabolism*
IF 2.999
Times Cited 32
Prokaryotes E. coli ME9062 (BW25113) Keio collection