Reference - Detail
| RRC ID | 35186 |
|---|---|
| Author | Tenorio E, Saeki T, Fujita K, Kitakawa M, Baba T, Mori H, Isono K. |
| Title | Systematic characterization of Escherichia coli genes/ORFs affecting biofilm formation. |
| Journal | FEMS Microbiol Lett |
| Abstract |
To understand the nature and function of bacterial biofilm and the process of its formation, we have performed systematic screening of a complete set of Escherichia coli genes/open reading frames (ORFs) to identify those that affect biofilm development upon over-expression. In contrast to the biofilm of strain AG1 used as a control, some of the genes/ORFs when over-expressed led to the formation of an abnormal biofilm such as thin, mat-like, filamentous or one easily detaching from various surfaces. Disruptants of selected genes were constructed in order to clarify their roles in the different stages of biofilm formation. Our results suggest that diverse metabolic pathways contribute to the development of biofilm. |
| Volume | 225(1) |
| Pages | 107-14 |
| Published | 2003-8-8 |
| DOI | 10.1016/S0378-1097(03)00507-X |
| PII | S037810970300507X |
| PMID | 12900028 |
| MeSH | Bacterial Outer Membrane Proteins / genetics Biofilms / growth & development* Escherichia coli / genetics* Escherichia coli / physiology* Fimbriae, Bacterial / genetics Gene Expression Genes, Bacterial* Mutagenesis Open Reading Frames Phenotype |
| IF | 1.987 |
| Times Cited | 28 |
| WOS Category | MICROBIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 3 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Prokaryotes E. coli | ME5305(AG1)? |