論文 - 詳細
RRC ID | 3634 |
---|---|
著者 | Sun H, Nelms BL, Sleiman SF, Chamberlin HM, Hanna-Rose W. |
タイトル | Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related Zinc-Finger ZIM proteins. |
ジャーナル | Genetics |
Abstract |
The previously reported negative regulatory activity of HIM-8 on the Sox protein EGL-13 is shared by the HIM-8-related ZIM proteins. Furthermore, mutation of HIM-8 can modulate the effects of substitution mutations in the DNA-binding domains of at least four other transcription factors, suggesting broad regulatory activity by HIM-8. |
巻・号 | 177(2) |
ページ | 1221-6 |
公開日 | 2007-10-1 |
DOI | 10.1534/genetics.107.070847 |
PII | genetics.107.070847 |
PMID | 17720937 |
PMC | PMC2034626 |
MeSH | Amino Acid Substitution Animals Caenorhabditis elegans Proteins / genetics* Caenorhabditis elegans Proteins / physiology Cell Cycle Proteins / genetics Cell Cycle Proteins / physiology* Chromosomal Proteins, Non-Histone / physiology* DNA-Binding Proteins / genetics Gene Expression Regulation Genes, Helminth Transcription Factors / physiology* Zinc Fingers |
IF | 4.015 |
引用数 | 7 |
WOS 分野 | GENETICS & HEREDITY |
リソース情報 | |
線虫 | tm1813 tm574 tm2303 tm607 tm611 |