RRC ID 36363
Author Nwibo DD, Hamamoto H, Matsumoto Y, Kaito C, Sekimizu K.
Title Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research.
Journal Drug Discov Ther
Abstract We advocate the use of silkworm larvae, Bombyx mori, as an animal model for discovery of drug candidates. We have established several disease models using silkworms, which offer technical advantages in drug development and the study of host-pathogen interaction. This mini review briefly describes recent trends in the use of silkworm larvae as a non-mammalian model for drug discovery and it offers suggestions regarding the potential for silkworm use in pharmaceutical-biomedical research.
Volume 9(2)
Pages 133-5
Published 2015-4-1
DOI 10.5582/ddt.2015.01026
PMID 25994065
MeSH Animals Anti-Bacterial Agents / pharmacology Biomedical Research* Bombyx* Drug Discovery* Hypoglycemic Agents / pharmacology Larva Models, Animal
Times Cited 16
Resource
Silkworms