Reference - Detail
| RRC ID | 3764 |
|---|---|
| Author | Inoue A, Murata Y, Takahashi H, Tsuji N, Fujisaki S, Kato J. |
| Title | Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli. |
| Journal | J Bacteriol |
| Abstract |
We isolated a temperature-sensitive mutant with a mutation in mviN, an essential gene in Escherichia coli. At the nonpermissive temperature, mviN mutant cells swelled and burst. An intermediate in murein synthesis, polyprenyl diphosphate-N-acetylmuramic acid-(pentapeptide)-N-acetyl-glucosamine, accumulated in mutant cells. These results indicated that MviN is involved in murein synthesis. |
| Volume | 190(21) |
| Pages | 7298-301 |
| Published | 2008-11-1 |
| DOI | 10.1128/JB.00551-08 |
| PII | JB.00551-08 |
| PMID | 18708495 |
| PMC | PMC2580715 |
| MeSH | Base Sequence Carbon Radioisotopes Diaminopimelic Acid / metabolism Escherichia coli / genetics Escherichia coli / metabolism* Escherichia coli Proteins / genetics Escherichia coli Proteins / metabolism* Genes, Essential / genetics Hemiterpenes / metabolism Models, Genetic Molecular Sequence Data Mutation Organophosphorus Compounds / metabolism Peptidoglycan / biosynthesis* Temperature |
| IF | 3.006 |
| Times Cited | 57 |
| WOS Category | MICROBIOLOGY |
| Resource | |
| INFORMATION | PEC |