RRC ID 38100
Author Ferris P, Olson BJ, De Hoff PL, Douglass S, Casero D, Prochnik S, Geng S, Rai R, Grimwood J, Schmutz J, Nishii I, Hamaji T, Nozaki H, Pellegrini M, Umen JG.
Title Evolution of an expanded sex-determining locus in Volvox.
Journal Science
Abstract Although dimorphic sexes have evolved repeatedly in multicellular eukaryotes, their origins are unknown. The mating locus (MT) of the sexually dimorphic multicellular green alga Volvox carteri specifies the production of eggs and sperm and has undergone a remarkable expansion and divergence relative to MT from Chlamydomonas reinhardtii, which is a closely related unicellular species that has equal-sized gametes. Transcriptome analysis revealed a rewired gametic expression program for Volvox MT genes relative to Chlamydomonas and identified multiple gender-specific and sex-regulated transcripts. The retinoblastoma tumor suppressor homolog MAT3 is a Volvox MT gene that displays sexually regulated alternative splicing and evidence of gender-specific selection, both of which are indicative of cooption into the sexual cycle. Thus, sex-determining loci affect the evolution of both sex-related and non-sex-related genes.
Volume 328(5976)
Pages 351-4
Published 2010-4-16
DOI 10.1126/science.1186222
PII 328/5976/351
PMID 20395508
PMC PMC2880461
MeSH Algal Proteins / genetics* Algal Proteins / metabolism Alternative Splicing Cell Division Chlamydomonas / genetics Chlamydomonas / physiology Evolution, Molecular* Gene Expression Profiling Gene Expression Regulation Genes* Genes, Retinoblastoma Genetic Loci* Introns Molecular Sequence Data Protozoan Proteins / genetics Protozoan Proteins / metabolism Recombination, Genetic Reproduction Retinoblastoma Protein / genetics Retinoblastoma Protein / metabolism Sequence Analysis, DNA Volvox / genetics* Volvox / physiology*
IF 41.846
Times Cited 95
Algae NIES-732 NIES-733