論文 - 詳細
| RRC ID | 38167 |
|---|---|
| 著者 | Ajiro H, Akashi M. |
| タイトル | Cell proliferation on stereoregular isotactic-poly(propylene oxide) as a bulk substrate. |
| ジャーナル | Biomacromolecules |
| Abstract |
Stereoregular isotactic-poly(propylene oxide) (it-PPO) was investigated for use as a biomaterial surface. The conventional characteristic of nonstereoregular atactic PPO was altered to a hydrophobic solid nature (contact angle: 95.6 ± 3.8°), which resulted in the potential solid surface applications. The high crystallinity of it-PPO created both smooth and microsized, random crater-shaped surfaces using the spin coating and dip coating approaches, respectively. The results of protein adsorption with bovine serum albumin (BSA), bovine gamma globulin (BγG), and bovine plasma fibrinogen (BPF) showed multilayered adsorption onto it-PPO. Mouse fibroblast L929 cells adhered onto the it-PPO surfaces, and cultured well as compared with commercially available Cell Desk LF1 as a control surface. These unique physical characteristics of it-PPO were due to the configuration of the polymer chain backbone structure, which maintained the polyether chemical structure. |
| 巻・号 | 11(11) |
| ページ | 2840-4 |
| 公開日 | 2010-11-8 |
| DOI | 10.1021/bm100926p |
| PMID | 20923199 |
| MeSH | Adsorption Animals Cattle Cell Adhesion Cell Proliferation Cells, Cultured Fibrinogen / chemistry* Mice Molecular Conformation Particle Size Polymers / chemistry* Propylene Glycols / chemistry* Serum Albumin, Bovine / chemistry* Stereoisomerism Surface Properties gamma-Globulins / chemistry* |
| IF | 6.092 |
| 引用数 | 6 |
| WOS 分野 | POLYMER SCIENCE CHEMISTRY, ORGANIC BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| ヒト・動物細胞 | |