論文 - 詳細
| RRC ID | 38653 |
|---|---|
| 著者 | Ito M, Maruhashi M, Sakai N, Mizoue K, Hanada K. |
| タイトル | NG-011 and NG-012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties. |
| ジャーナル | J Antibiot (Tokyo) |
| Abstract |
NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12). |
| 巻・号 | 45(10) |
| ページ | 1559-65 |
| 公開日 | 1992-10-1 |
| DOI | 10.7164/antibiotics.45.1559 |
| PMID | 1473982 |
| MeSH | Animals Anti-Bacterial Agents / pharmacology* Cells, Cultured Coumarins / chemistry Coumarins / isolation & purification Coumarins / pharmacology Isocoumarins Lactones / chemistry Lactones / isolation & purification Lactones / pharmacology* Nerve Growth Factors / pharmacology* Neurites / drug effects* PC12 Cells Penicillium* / chemistry Penicillium* / classification Penicillium* / isolation & purification Phenols / chemistry Phenols / isolation & purification Phenols / pharmacology* Rats |
| IF | 2.668 |
| 引用数 | 23 |
| WOS 分野 | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | PC-12(RCB0009) |