論文 - 詳細
| RRC ID | 39401 |
|---|---|
| 著者 | Kanemura Y, Hiraga S, Arita N, Ohnishi T, Izumoto S, Mori K, Matsumura H, Yamasaki M, Fushiki S, Yoshimine T. |
| タイトル | Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene. |
| ジャーナル | FEBS Lett |
| Abstract |
A novel human homologue (GCMB) of the Drosophila glial cells missing gene (dGCM) was isolated using RACE. GCMB contained a gcm motif sequence and a nuclear targeting sequence similar to that of dGCM and mouse GCMb. Homology searches indicated that GCMB was located within chromosome 6p24.2. Transcripts of GCMB were detected by means of RT-PCR in fetal brain, normal adult kidney, 3/3 medulloblastomas, 1/3 gliomas and 4/8 non-neuroepithelial tumor cell lines. Our data suggest that humans have two homologues of gcm like mice and that human gcm genes form a novel family which may function not only during fetal development but also in the postnatal or pathological stage. |
| 巻・号 | 442(2-3) |
| ページ | 151-6 |
| 公開日 | 1999-1-15 |
| DOI | 10.1016/s0014-5793(98)01650-0 |
| PII | S0014-5793(98)01650-0 |
| PMID | 9928992 |
| MeSH | Amino Acid Sequence Animals Base Sequence Blotting, Southern Brain / embryology Brain / metabolism* Chromosomes, Human, Pair 6 / genetics Cloning, Molecular* DNA-Binding Proteins Drosophila Proteins Drosophila melanogaster / genetics Expressed Sequence Tags Gene Expression* Gene Library Humans Kidney / metabolism Molecular Sequence Data Neoplasms, Neuroepithelial / metabolism Neuropeptides / chemistry Neuropeptides / genetics* Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology, Nucleic Acid Trans-Activators / chemistry Trans-Activators / genetics* Transcription Factors Tumor Cells, Cultured |
| IF | 3.057 |
| 引用数 | 45 |
| WOS 分野 | BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Wikipedia |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | U251(RCB0461) |