RRC ID 40999
著者 Ishii T, Nonaka K, Sugawara A, Iwatsuki M, Masuma R, Hirose T, Sunazuka T, Ōmura S, Shiomi K.
タイトル Cinatrins D and E, and virgaricin B, three novel compounds produced by a fungus, Virgaria boninensis FKI-4958.
ジャーナル J Antibiot (Tokyo)
Abstract Two new hydroxycitric acid lactone derivatives named cinatrins D (1) and E (2), and a new γ-lactam, virgaricin B (3), along with a known similar compound, virgaricin (4), were isolated from a fermentation broth of the fungus Virgaria boninensis FKI-4958. The absolute stereo structures of the new compounds were established by a combination of spectroscopic methods and chemical modifications. All three newly discovered compounds possessed weak antibacterial activity.
巻・号 68(10)
ページ 633-7
公開日 2015-10-1
DOI 10.1038/ja.2015.45
PII ja201545
PMID 25899122
MeSH Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification Anti-Bacterial Agents / pharmacology* Ascomycota / chemistry* Bacteria / drug effects Citrates / chemistry Citrates / isolation & purification Citrates / pharmacology* Fermentation Lactams / chemistry Lactams / isolation & purification Lactams / pharmacology* Lactones / chemistry Lactones / isolation & purification Lactones / pharmacology* Microbial Sensitivity Tests Molecular Conformation Soil Microbiology
IF 2.668
引用数 6
WOS 分野 PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY IMMUNOLOGY
リソース情報
一般微生物 JCM 18623 JCM 18624