RRC ID 41451
著者 Teratani T, Watanabe T, Kuwahara F, Kumagai H, Kobayashi S, Aoki U, Ishikawa A, Arai K, Nozawa R.
タイトル Induced transcriptional expression of calcium-binding protein S100A1 and S100A10 genes in human renal cell carcinoma.
ジャーナル Cancer Lett
Abstract Expression of 16 S100 family calcium-binding protein genes was evaluated by PCR in ten human tissue cDNA libraries. Six to 12 S100 genes were expressed in a tissue-specific manner. Then, the expression in the surgically resected renal cell carcinoma (RCC) and a cultured RCC cell line was studied by RT-PCR. Although eight to nine S100 genes were transcribed in the normal kidney library and non-cancerous part of resected kidney tumors, S100A1 and S100A10 genes were not expressed. However, these genes were newly expressed in the RCC lesions (n=7) and the RCC cell line, indicating that expression of S100A1 and S100A10 genes is accompanied by RCC.
巻・号 175(1)
ページ 71-7
公開日 2002-1-10
DOI 10.1016/s0304-3835(01)00724-8
PII S0304383501007248
PMID 11734338
MeSH Annexin A2* Base Sequence Calcium-Binding Proteins / genetics* Carcinoma, Renal Cell / genetics* DNA Primers Gene Amplification Gene Expression Regulation, Neoplastic Gene Library Humans Kidney / metabolism Kidney Neoplasms / genetics* Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction S100 Proteins* Transcription, Genetic*
IF 7.36
引用数 41
WOS 分野 ONCOLOGY
リソース情報
ヒト・動物細胞 TUHR14TKB(RCB1383)