| RRC ID |
41451
|
| 著者 |
Teratani T, Watanabe T, Kuwahara F, Kumagai H, Kobayashi S, Aoki U, Ishikawa A, Arai K, Nozawa R.
|
| タイトル |
Induced transcriptional expression of calcium-binding protein S100A1 and S100A10 genes in human renal cell carcinoma.
|
| ジャーナル |
Cancer Lett
|
| Abstract |
Expression of 16 S100 family calcium-binding protein genes was evaluated by PCR in ten human tissue cDNA libraries. Six to 12 S100 genes were expressed in a tissue-specific manner. Then, the expression in the surgically resected renal cell carcinoma (RCC) and a cultured RCC cell line was studied by RT-PCR. Although eight to nine S100 genes were transcribed in the normal kidney library and non-cancerous part of resected kidney tumors, S100A1 and S100A10 genes were not expressed. However, these genes were newly expressed in the RCC lesions (n=7) and the RCC cell line, indicating that expression of S100A1 and S100A10 genes is accompanied by RCC.
|
| 巻・号 |
175(1)
|
| ページ |
71-7
|
| 公開日 |
2002-1-10
|
| DOI |
10.1016/s0304-3835(01)00724-8
|
| PII |
S0304383501007248
|
| PMID |
11734338
|
| MeSH |
Annexin A2*
Base Sequence
Calcium-Binding Proteins / genetics*
Carcinoma, Renal Cell / genetics*
DNA Primers
Gene Amplification
Gene Expression Regulation, Neoplastic
Gene Library
Humans
Kidney / metabolism
Kidney Neoplasms / genetics*
Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
S100 Proteins*
Transcription, Genetic*
|
| IF |
7.36
|
| 引用数 |
41
|
|
WOS 分野
|
ONCOLOGY
|
| リソース情報 |
| ヒト・動物細胞 |
TUHR14TKB(RCB1383) |
