RRC ID 41940
著者 Ohguchi K, Tanaka T, Ito T, Iinuma M, Matsumoto K, Akao Y, Nozawa Y.
タイトル Inhibitory effects of resveratrol derivatives from dipterocarpaceae plants on tyrosinase activity.
ジャーナル Biosci Biotechnol Biochem
Abstract Stilbene derivatives, which are resveratrol (3,4',5-trihydroxy-trans-stilbene) oligomers ranging from monomer to tetramer, isolated from Dipterocarpaceae plants were tested for their inhibitory effects against murine tyrosinase activity. The structure-activity relationships obtained in this study suggest that the double bond in the stilbene skeleton is critical for the inhibition, and also that molecular size is important for inhibitory potency.
巻・号 67(7)
ページ 1587-9
公開日 2003-7-1
DOI 10.1271/bbb.67.1587
PMID 12913307
MeSH Animals Cell Line, Tumor Enzyme Inhibitors / chemistry Enzyme Inhibitors / pharmacology* Ericales / chemistry* Mice Molecular Structure Monophenol Monooxygenase / antagonists & inhibitors* Monophenol Monooxygenase / metabolism Pyrones / chemistry Pyrones / pharmacology Resveratrol Stilbenes / chemistry Stilbenes / pharmacology* Structure-Activity Relationship
IF 1.516
引用数 52
WOS 分野 CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
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リソース情報
ヒト・動物細胞 B16 melanoma