| RRC ID |
41940
|
| 著者 |
Ohguchi K, Tanaka T, Ito T, Iinuma M, Matsumoto K, Akao Y, Nozawa Y.
|
| タイトル |
Inhibitory effects of resveratrol derivatives from dipterocarpaceae plants on tyrosinase activity.
|
| ジャーナル |
Biosci Biotechnol Biochem
|
| Abstract |
Stilbene derivatives, which are resveratrol (3,4',5-trihydroxy-trans-stilbene) oligomers ranging from monomer to tetramer, isolated from Dipterocarpaceae plants were tested for their inhibitory effects against murine tyrosinase activity. The structure-activity relationships obtained in this study suggest that the double bond in the stilbene skeleton is critical for the inhibition, and also that molecular size is important for inhibitory potency.
|
| 巻・号 |
67(7)
|
| ページ |
1587-9
|
| 公開日 |
2003-7-1
|
| DOI |
10.1271/bbb.67.1587
|
| PMID |
12913307
|
| MeSH |
Animals
Cell Line, Tumor
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Ericales / chemistry*
Mice
Molecular Structure
Monophenol Monooxygenase / antagonists & inhibitors*
Monophenol Monooxygenase / metabolism
Pyrones / chemistry
Pyrones / pharmacology
Resveratrol
Stilbenes / chemistry
Stilbenes / pharmacology*
Structure-Activity Relationship
|
| IF |
1.516
|
| 引用数 |
52
|
|
WOS 分野
|
CHEMISTRY, APPLIED
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| リソース情報 |
| ヒト・動物細胞 |
B16 melanoma |
