RRC ID 43325
著者 Ohguchi K, Koike M, Suwa Y, Koshimizu S, Mizutani Y, Nozawa Y, Akao Y.
タイトル Inhibitory effects of whisky congeners on melanogenesis in mouse B16 melanoma cells.
ジャーナル Biosci Biotechnol Biochem
Abstract We examined the effect of whisky congeners, substances other than ethanol in whisky, on melanogenesis in mouse B16 melanoma cells. Treatment with whisky congeners significantly blocked melanogenesis. Our results indicate that the inhibitory effects of whisky congeners on melanogenesis is due to direct inhibition of tyrosinase activity and to suppression of tyrosinase protein levels.
巻・号 72(4)
ページ 1107-10
公開日 2008-4-1
DOI 10.1271/bbb.70734
PII JST.JSTAGE/bbb/70734
PMID 18391453
MeSH Alcoholic Beverages* / analysis Animals Cattle Cell Line, Tumor Flavonoids / pharmacology* Gene Expression Regulation, Neoplastic / drug effects Melanins / biosynthesis* Melanoma, Experimental / metabolism* Mice Monophenol Monooxygenase / metabolism Phenols / pharmacology* Polyphenols alpha-MSH / pharmacology
IF 1.516
引用数 8
WOS 分野 FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
ヒト・動物細胞