RRC ID 44467
Author Kawamura E, Yamada Y, Yasuzaki Y, Hyodo M, Harashima H.
Title Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide.
Journal J Biosci Bioeng
Abstract This study focused on the intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide (MTS). The nanocarriers showed an efficient cellular uptake, and the MTS had a positive effect on their mitochondrial targeting. This is the first report of an intracellular observation of nanocarriers modified with MTS.
Volume 116(5)
Pages 634-7
Published 2013-11-1
DOI 10.1016/j.jbiosc.2013.05.001
PII S1389-1723(13)00164-3
PMID 23735326
MeSH Drug Carriers / analysis Drug Carriers / metabolism Drug Delivery Systems HeLa Cells Humans Intracellular Space / metabolism* Mitochondria / metabolism* Nanomedicine Nanostructures / analysis* Nanostructures / chemistry Protein Sorting Signals* Substrate Specificity
IF 2.366
Times Cited 20
WOS Category FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Resource
Human and Animal Cells HeLa