論文 - 詳細
| RRC ID | 44467 |
|---|---|
| 著者 | Kawamura E, Yamada Y, Yasuzaki Y, Hyodo M, Harashima H. |
| タイトル | Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide. |
| ジャーナル | J Biosci Bioeng |
| Abstract |
This study focused on the intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide (MTS). The nanocarriers showed an efficient cellular uptake, and the MTS had a positive effect on their mitochondrial targeting. This is the first report of an intracellular observation of nanocarriers modified with MTS. |
| 巻・号 | 116(5) |
| ページ | 634-7 |
| 公開日 | 2013-11-1 |
| DOI | 10.1016/j.jbiosc.2013.05.001 |
| PII | S1389-1723(13)00164-3 |
| PMID | 23735326 |
| MeSH | Drug Carriers / analysis Drug Carriers / metabolism Drug Delivery Systems HeLa Cells Humans Intracellular Space / metabolism* Mitochondria / metabolism* Nanomedicine Nanostructures / analysis* Nanostructures / chemistry Protein Sorting Signals* Substrate Specificity |
| IF | 2.366 |
| 引用数 | 20 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | HeLa |