Reference - Detail
| RRC ID | 46552 |
|---|---|
| Author | Zhuang JJ, Hunter CP. |
| Title | Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. |
| Journal | Genetics |
| Abstract |
Gene knockdown by RNA interference (RNAi) in Caenorhabditis elegans is readily achieved by feeding bacteria expressing double-stranded RNA (dsRNA). Enhanced RNAi (Eri) mutants facilitate RNAi due to their hypersensitivity to dsRNA. Here, we compare eight Eri mutants for sensitivity to ingested dsRNA, targeting a variety of tissue-specific genes. |
| Volume | 188(1) |
| Pages | 235-7 |
| Published | 2011-5-1 |
| DOI | 10.1534/genetics.111.127209 |
| PII | genetics.111.127209 |
| PMID | 21385728 |
| PMC | PMC3120140 |
| MeSH | Animals Caenorhabditis elegans / genetics* Genetic Testing Mutation / genetics* Organ Specificity / genetics* Phenotype RNA Interference* RNA, Double-Stranded / metabolism |
| IF | 4.015 |
| Times Cited | 25 |
| WOS Category | GENETICS & HEREDITY |
| Resource | |
| C.elegans | tm1361 tm1705 tm1917 tm1860 |