| RRC ID |
47043
|
| Author |
Ogawa S, Shibahara T, Sano A, Kadota K, Kubo M.
|
| Title |
Generalized hyperkeratosis caused by Scopulariopsis brevicaulis in a Japanese Black calf.
|
| Journal |
J Comp Pathol
|
| Abstract |
A 6-month-old Japanese Black female calf became gradually emaciated over a 40-day period and was humanely killed. At necropsy, hyperkeratotic nodules were seen to have spread over almost the entire body surface. Scopulariopsis brevicaulis was isolated from the skin and identified morphologically and by gene sequence analysis of the D1/D2 domain of large subunit ribosomal RNA. Numerous periodic acid-Schiff-positive, lemon-shaped conidia were detected histologically in the keratinized layer and the hair follicles. The distribution of the fungal elements in the skin corresponded to that of the hyperkeratotic lesions. This is the first report of a disease caused by S. brevicaulis in animals. Previously reported human infections have not included generalized hyperkeratosis.
|
| Volume |
138(2-3)
|
| Pages |
145-50
|
| Published |
2008-1-1
|
| DOI |
10.1016/j.jcpa.2007.10.004
|
| PII |
S0021-9975(07)00161-2
|
| PMID |
18295781
|
| MeSH |
Animals
Antibodies, Fungal / analysis
Ascomycota / genetics
Ascomycota / immunology
Ascomycota / isolation & purification*
Cattle
Cattle Diseases / drug therapy
Cattle Diseases / microbiology*
Drug Therapy, Combination
Euthanasia, Animal
Fatal Outcome
Female
Keratosis / drug therapy
Keratosis / microbiology
Keratosis / veterinary*
Mycoses / drug therapy
Mycoses / pathology
Mycoses / veterinary*
Periodic Acid-Schiff Reaction
RNA, Fungal / analysis
RNA, Ribosomal / analysis
Skin / metabolism
Skin / microbiology
Skin / pathology*
|
| IF |
0.994
|
| Times Cited |
3
|
|
WOS Category
|
VETERINARY SCIENCES
PATHOLOGY
|
| Resource |
| Pathogenic microorganisms |
NA |
