RRC ID 47043
著者 Ogawa S, Shibahara T, Sano A, Kadota K, Kubo M.
タイトル Generalized hyperkeratosis caused by Scopulariopsis brevicaulis in a Japanese Black calf.
ジャーナル J Comp Pathol
Abstract A 6-month-old Japanese Black female calf became gradually emaciated over a 40-day period and was humanely killed. At necropsy, hyperkeratotic nodules were seen to have spread over almost the entire body surface. Scopulariopsis brevicaulis was isolated from the skin and identified morphologically and by gene sequence analysis of the D1/D2 domain of large subunit ribosomal RNA. Numerous periodic acid-Schiff-positive, lemon-shaped conidia were detected histologically in the keratinized layer and the hair follicles. The distribution of the fungal elements in the skin corresponded to that of the hyperkeratotic lesions. This is the first report of a disease caused by S. brevicaulis in animals. Previously reported human infections have not included generalized hyperkeratosis.
巻・号 138(2-3)
ページ 145-50
公開日 2008-1-1
DOI 10.1016/j.jcpa.2007.10.004
PII S0021-9975(07)00161-2
PMID 18295781
MeSH Animals Antibodies, Fungal / analysis Ascomycota / genetics Ascomycota / immunology Ascomycota / isolation & purification* Cattle Cattle Diseases / drug therapy Cattle Diseases / microbiology* Drug Therapy, Combination Euthanasia, Animal Fatal Outcome Female Keratosis / drug therapy Keratosis / microbiology Keratosis / veterinary* Mycoses / drug therapy Mycoses / pathology Mycoses / veterinary* Periodic Acid-Schiff Reaction RNA, Fungal / analysis RNA, Ribosomal / analysis Skin / metabolism Skin / microbiology Skin / pathology*
IF 0.994
引用数 3
WOS 分野 VETERINARY SCIENCES PATHOLOGY
リソース情報
病原微生物 NA