論文 - 詳細
| RRC ID | 4912 |
|---|---|
| 著者 | Inoue T, Shingaki R, Hirose S, Waki K, Mori H, Fukui K. |
| タイトル | Genome-wide screening of genes required for swarming motility in Escherichia coli K-12. |
| ジャーナル | J Bacteriol |
| Abstract |
Escherichia coli K-12 has the ability to migrate on semisolid media by means of swarming motility. A systematic and comprehensive collection of gene-disrupted E. coli K-12 mutants (the Keio collection) was used to identify the genes involved in the swarming motility of this bacterium. Of the 3,985 nonessential gene mutants, 294 were found to exhibit a strongly repressed-swarming phenotype. Further, 216 of the 294 mutants displayed no significant defects in swimming motility; therefore, the 216 genes were considered to be specifically associated with the swarming phenotype. The swarming-associated genes were classified into various functional categories, indicating that swarming is a specialized form of motility that requires a wide variety of cellular activities. These genes include genes for tricarboxylic acid cycle and glucose metabolism, iron acquisition, chaperones and protein-folding catalysts, signal transduction, and biosynthesis of cell surface components, such as lipopolysaccharide, the enterobacterial common antigen, and type 1 fimbriae. Lipopolysaccharide and the enterobacterial common antigen may be important surface-acting components that contribute to the reduction of surface tension, thereby facilitating the swarm migration in the E. coli K-12 strain. |
| 巻・号 | 189(3) |
| ページ | 950-7 |
| 公開日 | 2007-2-1 |
| DOI | 10.1128/JB.01294-06 |
| PII | JB.01294-06 |
| PMID | 17122336 |
| PMC | PMC1797309 |
| MeSH | Antigens, Bacterial / genetics Antigens, Bacterial / physiology Citric Acid Cycle / genetics Citric Acid Cycle / physiology Escherichia coli / genetics* Escherichia coli / physiology Escherichia coli / ultrastructure Escherichia coli Proteins / chemistry Escherichia coli Proteins / genetics* Escherichia coli Proteins / physiology Fimbriae, Bacterial / chemistry Fimbriae, Bacterial / genetics Fimbriae, Bacterial / physiology Gene Deletion Genes, Bacterial* Genome, Bacterial* Glucose / metabolism Microscopy, Electron, Transmission Molecular Chaperones / genetics Molecular Chaperones / physiology Polysaccharides, Bacterial / metabolism Protein Folding Signal Transduction / genetics Signal Transduction / physiology |
| IF | 3.006 |
| 引用数 | 122 |
| WOS 分野 | MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 原核生物(大腸菌) | Keno collection |