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  • Search Condition : Filter (MeSH = Signal Transduction / genetics)
Species Resource Title
Human and Animal Cells KGN(RCB1154) A novel CUL4B gene variant activating Wnt4/β-catenin signal pathway to karyotype 46, XY female with disorders of sex development.
DNA material pKM2L-phKIT (RDB05812) , pKM2L (RDB04026) SCF (Stem Cell Factor) and cKIT Modulate Pathological Ocular Neovascularization.
Human and Animal Cells PANC-1(RCB2095) Role of miR-30a-3p Regulation of Oncogenic Targets in Pancreatic Ductal Adenocarcinoma Pathogenesis.
Zebrafish UAS:GFP Vegfa signals through ERK to promote angiogenesis, but not artery differentiation.
Drosophila DGRC#119186 , DGRC#119187 Expression of Human Mutant Preproinsulins Induced Unfolded Protein Response, Gadd45 Expression, JAK-STAT Activation, and Growth Inhibition in Drosophila.
C.elegans tm1714 , tm15936 , tm2265 , tm2001 , tm8184 Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways.
Prokaryotes E. coli ME9997 , ME9998 , ME9999 , ME10000 , ME10001 , ME10002 , ME10003 , ME10004 , ME10005 A putrescine-inducible pathway comprising PuuE-YneI in which gamma-aminobutyrate is degraded into succinate in Escherichia coli K-12.
Drosophila Functional opsin patterning for Drosophila color vision is established through signaling pathways in adjacent object-detection neurons.
Mice RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
Arabidopsis / Cultured plant cells, genes psi00187 , psi00188 , psi00189 S1 basic leucine zipper transcription factors shape plant architecture by controlling C/N partitioning to apical and lateral organs.
Human and Animal Cells SH-10-TC(RCB1940) Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Human and Animal Cells ST2(RCB0224) Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling.
Human and Animal Cells OP9(RCB1124) A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.
Human and Animal Cells COLO-320(RCB1193) , LoVo(RCB1639) Tumor suppressor miR-193a-3p enhances efficacy of BRAF/MEK inhibitors in BRAF-mutated colorectal cancer.
C.elegans tm810 Discovery of nonautonomous modulators of activated Ras.
C.elegans tm4397 , tm4212 ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.
C.elegans tm10640 Caenorhabditis elegans PTR/PTCHD PTR-18 promotes the clearance of extracellular hedgehog-related protein via endocytosis.
Zebrafish SAGFF(LF)27C , UAS:GFP Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2.
Zebrafish UAS:GFP Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling.
Zebrafish hspGFFDMC72A Neuron and sensory epithelial cell fate is sequentially determined by Notch signaling in zebrafish lateral line development.