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  • Search Condition : Filter (MeSH = Protein Folding)
Species Resource Title
DNA material Genome Network Project Human cDNA , IRAL021H13 (HGY088581) , IRAK004A12 (HGX001612) S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.
Drosophila The transcription factor Dysfusion promotes fold and joint morphogenesis through regulation of Rho1.
Human and Animal Cells 293(RCB1637) Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
Prokaryotes E. coli BW25113, ∆degP, ∆hdeA, and ∆degQ DegP functions as a critical protease for bacterial acid resistance.
Human and Animal Cells 293T(RCB2202) Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.
Drosophila Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration.
C.elegans tm1180 Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway.
DNA material CMV:TDP43-GFP (RDB15742) , CMV:GFP-TDP25 (RDB15743) , CMV:GFP-NLS-TDP25 (RDB15744) , CMV:GFP-NLSNP-TDP25 (RDB15745) , GFP-NLS NP (RDB15746) , mCherry-Ubiquitin (RDB15747). Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
DNA material Xpa (RDB15264) , Xpa H62Q (RDB15265). A diffraction-quality protein crystal processed as an autophagic cargo.
Drosophila 3936-R2 Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna.
Mice GFP-LC3#53(RBRC00806) Sequestosome 1 (SQSTM1/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture.
Arabidopsis / Cultured plant cells, genes pda10975 , pda02804 , pda06312 , pda12960 , pda02458 , pda05667 Folding of intrinsically disordered plant LEA proteins is driven by glycerol-induced crowding and the presence of membranes.
Arabidopsis / Cultured plant cells, genes pda12225 , pda04013 Systematic deletion of the ER lectin chaperone genes reveals their roles in vegetative growth and male gametophyte development in Arabidopsis.
Yeast , Human and Animal Cells FYC550(psk1)? , MCF7(RCB1904) , 293T(RCB2202) Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.
C.elegans tm843 , tm2183 , tm1920 The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans.
C.elegans tm1380 , tm2915 , tm1349 , tm544 A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans.
C.elegans tm1453 Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex.
C.elegans tm4525 Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2.
C.elegans tm1011 Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood.
C.elegans tm847 , tm3790 , tm1320 Derlin-dependent retrograde transport from endosomes to the Golgi apparatus.