論文 - 詳細
| RRC ID | 52856 |
|---|---|
| 著者 | Shinkai Y, Yoshida MC, Maeda K, Kobata T, Maruyama K, Yodoi J, Yagita H, Okumura K. |
| タイトル | Molecular cloning and chromosomal assignment of a human perforin (PFP) gene. |
| ジャーナル | Immunogenetics |
| Abstract |
Human perforin cDNA was isolated and the complete nucleotide sequence of the gene determined. The deduced amino acid sequence of human perforin showed 68.4% similarity to that of mouse perforin. RNA blot analysis of the human perforin gene revealed that the gene product is expressed preferentially in killer-type cells among cell lines tested, and in large granular lymphocytes among the peripheral blood mononuclear cells. In situ hybridization analysis with a human perforin cDNA probe revealed that the human perforin (PFP) gene is located on chromosome 17q11-21. |
| 巻・号 | 30(6) |
| ページ | 452-7 |
| 公開日 | 1989-1-1 |
| DOI | 10.1007/BF02421177 |
| PMID | 2592021 |
| MeSH | Base Sequence Blotting, Northern Chromosome Mapping* Chromosomes, Human, Pair 17 Cloning, Molecular* DNA / isolation & purification Humans Membrane Glycoproteins* Membrane Proteins / genetics* Molecular Sequence Data Perforin Pore Forming Cytotoxic Proteins |
| IF | 2.621 |
| 引用数 | 61 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Wikipedia |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 遺伝子材料 | YT101 (RDB01181). |