RRC ID 53640
著者 Suzuki K, Moriguchi K, Yamamoto S.
タイトル Horizontal DNA transfer from bacteria to eukaryotes and a lesson from experimental transfers.
ジャーナル Res Microbiol
Abstract Horizontal gene transfer (HGT) is widespread among bacteria and plays a key role in genome dynamics. HGT is much less common in eukaryotes, but is being reported with increasing frequency in eukaryotes. The mechanism as to how eukaryotes acquired genes from distantly related organisms remains obscure yet. This paper cites examples of bacteria-derived genes found in eukaryotic organisms, and then describes experimental DNA transports to eukaryotes by bacterial type 4 secretion systems in optimized conditions. The mechanisms of the latter are efficient, quite reproducible in vitro and predictable, and thereby would provide insight into natural HGT and to the development of new research tools.
巻・号 166(10)
ページ 753-63
公開日 2015-12-1
DOI 10.1016/j.resmic.2015.08.001
PII S0923-2508(15)00130-8
PMID 26291765
MeSH Animals Bacteria / genetics* DNA, Bacterial / genetics Eukaryota / genetics* Evolution, Molecular Gene Transfer Techniques Gene Transfer, Horizontal* Genes, Bacterial* Phylogeny Type IV Secretion Systems / genetics Type IV Secretion Systems / metabolism
IF 3.217
引用数 4
リソース情報
原核生物(大腸菌)