RRC ID 54294
著者 International Wheat Genome Sequencing Consortium (IWGSC).
タイトル Shifting the limits in wheat research and breeding using a fully annotated reference genome.
ジャーナル Science
Abstract An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
巻・号 361(6403)
公開日 2018-8-17
DOI 10.1126/science.aar7191
PII 361/6403/eaar7191
PMID 30115783
MeSH Atlases as Topic Bread Breeding* Gene Expression Regulation, Developmental* Gene Expression Regulation, Plant* Genome, Plant* Molecular Sequence Annotation Multigene Family Phylogeny Quantitative Trait Loci Reference Standards Transcriptome Triticum / anatomy & histology Triticum / classification Triticum / genetics* Triticum / growth & development*
IF 41.846
引用数 503
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