RRC ID 55168
Author Kawashima T, Ikari N, Watanabe Y, Kubota Y, Yoshio S, Kanto T, Motohashi S, Shimojo N, Tsuji NM.
Title Double-Stranded RNA Derived from Lactic Acid Bacteria Augments Th1 Immunity via Interferon-β from Human Dendritic Cells.
Journal Front Immunol
Abstract DCs, DCs stimulated with LAB containing dsRNA induced IFN-γ-producing T cells. These results indicate that human DCs activated by LAB enhance Th1 immunity depending on IFN-β secretion in response to bacterial dsRNA.
Volume 9
Pages 27
Published 2018
DOI 10.3389/fimmu.2018.00027
PMID 29410667
PMC PMC5787129
MeSH Antigens, CD1 / metabolism Cells, Cultured Dendritic Cells / immunology* Glycoproteins / metabolism Humans Interferon-beta / biosynthesis Interferon-beta / immunology* Interferon-gamma / biosynthesis Interferon-gamma / immunology Interleukin-12 Subunit p35 / metabolism Lactobacillales / genetics Lactobacillales / immunology* RNA, Bacterial / immunology RNA, Double-Stranded / immunology* Th1 Cells / immunology* Th2 Cells / metabolism
IF 5.511
General Microbes JCM 1149 JCM 1558 JCM 5805 JCM 1002 JCM 1136 JCM 5824 JCM 5826 JCM 5827 JCM 9498