RRC ID 56243
Author Yuan P, Pan LY, Xiong LG, Tong JW, Li J, Huang JA, Gong YS, Liu ZH.
Title Black tea increases hypertonic stress resistance in C. elegans.
Journal Food Funct
Abstract Here we identified that BTE (black tea extract), within the studied concentration range, is more effective than GTE (green tea extract) in protecting C. elegans against hypertonic stress, by enhancing survival after exposure to various salts, and alleviating suffered motility loss and body shrinkage. The mechanism of such protection may be due to the ability of black tea to induce the conserved WNK/GCK signaling pathway and down-regulation of the expression levels of nlp-29. Intriguingly, black tea does not relieve hypertonicity-induced protein damage. The findings implicate the potential health benefits of black tea consumed worldwide.
Volume 9(7)
Pages 3798-3806
Published 2018-7-17
DOI 10.1039/c7fo02017a
PMID 29932178
MeSH Animals Caenorhabditis elegans / drug effects* Caenorhabditis elegans / genetics Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism Camellia sinensis / chemistry* Osmotic Pressure / drug effects* Plant Extracts / chemistry Plant Extracts / pharmacology* Signal Transduction / drug effects
IF 3.241
Times Cited 3
Resource
C.elegans