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  • Search Condition : Filter (MeSH = Signal Transduction / drug effects)
Species Resource Title
Human and Animal Cells MC3T3-E1(RCB1126) Gprc5a is a novel parathyroid hormone-inducible gene and negatively regulates osteoblast proliferation and differentiation.
Mice RBRC02332 , RBRC03111 Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors.
Human and Animal Cells , DNA material CACO-2(RCB0988) , pGL4-phTNF (RDB07310) , pGL4-phIL6 (RDB07313) Molecular Mechanisms of Skatole-Induced Inflammatory Responses in Intestinal Epithelial Caco-2 Cells: Implications for Colorectal Cancer and Inflammatory Bowel Disease.
Human and Animal Cells C2C12(RCB0987) Inflammatory Cytokine-Induced Muscle Atrophy and Weakness Can Be Ameliorated by an Inhibition of TGF-β-Activated Kinase-1.
Human and Animal Cells MIA Paca2(RCB2094) , PANC-1(RCB2095) FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells.
Human and Animal Cells CHO-K1(RCB0285) , HeLa((RCB0007) , A431(RCB0202) , Ba/F3(RCB4476) Single molecule tracking based drug screening.
Human and Animal Cells CACO-2(RCB0988) Effects of elafibranor on liver fibrosis and gut barrier function in a mouse model of alcohol-associated liver disease.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Development of Human CBF1-Targeting Single-Stranded DNA Aptamers with Antiangiogenic Activity In Vitro.
Arabidopsis / Cultured plant cells, genes pst14772 Stomatal immunity against fungal invasion comprises not only chitin-induced stomatal closure but also chitosan-induced guard cell death.
Mice RBRC01390 Urolithin A-mediated augmentation of intestinal barrier function through elevated secretory mucin synthesis.
Prokaryotes E. coli ME9997 , ME9998 , ME9999 , ME10000 , ME10001 , ME10002 , ME10003 , ME10004 , ME10005 A putrescine-inducible pathway comprising PuuE-YneI in which gamma-aminobutyrate is degraded into succinate in Escherichia coli K-12.
Human and Animal Cells C2C12(RCB0987) Carbon monoxide-loaded cell therapy as an exercise mimetic for sarcopenia treatment.
Human and Animal Cells RBE(RCB1292) , HuCCT1(RCB1960) SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma.
Human and Animal Cells HCT116(RCB2979) , Colon-26(RCB2657) Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains.
Mice RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
Human and Animal Cells SH-10-TC(RCB1940) Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Human and Animal Cells RMS-YM(RCB1695) Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Human and Animal Cells PC-12(RCB0009) Ca(2+) influx through P2X receptors induces actin cytoskeleton reorganization by the formation of cofilin rods in neurites.
Human and Animal Cells COLO-320(RCB1193) , LoVo(RCB1639) Tumor suppressor miR-193a-3p enhances efficacy of BRAF/MEK inhibitors in BRAF-mutated colorectal cancer.
Human and Animal Cells ATDC5(RCB0565) High-throughput screening for modulators of ACVR1 transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva.