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  • Search Condition : Filter (MeSH = Signal Transduction / drug effects)
Species Resource
Rats Chronic intracerebroventricular administration of relaxin-3 increases body weight in rats.
Human and Animal Cells CACO-2 Human breast milk suppresses the transcriptional regulation of IL-1beta-induced NF-kappaB signaling in human intestinal cells.
Human and Animal Cells MKN45 Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.
Human and Animal Cells K562 Inactivation of ERK accelerates erythroid differentiation of K562 cells induced by herbimycin A and STI571 while activation of MEK1 interferes with it.
Human and Animal Cells ATDC5 p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Human and Animal Cells GT3TKB Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
Human and Animal Cells MC3T3-E1 Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
Human and Animal Cells CTLL-2 A mechanism of induction of the mouse zinc-fingers and homeoboxes 1 (ZHX1) gene expression by interleukin-2.
Human and Animal Cells MKN7 , MKN45 , MKN74 COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines.
Human and Animal Cells Jurkat Carbohydrate chains and phosphatidylserine successively work as signals for apoptotic cell removal.
DNA material pHSP90 (RDB01127) Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox.
DNA material AxCALacZ (RDB1745) Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.
Yeast HM123 Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast.
C.elegans tm445 , tm501 Caenorhabditis elegans integrates the signals of butanone and food to enhance chemotaxis to butanone.
Human and Animal Cells Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: molecular mechanisms and structure-activity relationship.
Arabidopsis / Cultured plant cells, genes rpc00008  Modulation of defense signal transduction by flagellin-induced WRKY41 transcription factor in Arabidopsis thaliana.
C.elegans tm1325 An antidepressant that extends lifespan in adult Caenorhabditis elegans.
C.elegans tm1996 Functional characterization of three G protein-coupled receptors for pigment dispersing factors in Caenorhabditis elegans.
C.elegans tm331 Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity.
C.elegans tm748 Tissue-specific functions of the Caenorhabditis elegans p120 Ras GTPase activating protein GAP-3.