| RRC ID |
56465
|
| Author |
Takahashi A, Shibata N, Nishikawa S, Ohnishi K, Ishioka N, Ohnishi T.
|
| Title |
UV-B light induces an adaptive response to UV-C exposure via photoreactivation activity in Euglena gracilis.
|
| Journal |
Photochem Photobiol Sci
|
| Abstract |
Phytoplankton such as Euglena are constantly exposed to solar light which is used for photosynthesis. Although the solar ultraviolet (UV) induces DNA damage such as cyclobutane-pyrimidine dimers (CPDs), many kinds of living organisms can repair CPDs by photoreactivation (PR) utilizing the near-UV/blue light component in sunlight. Euglena cells are known to possess such PR activity. In the present paper, the formation of CPDs induced by UV-C exposure and the photoreactivation PR repair of these CPDs by UV-A are demonstrated. To clarify the adaptive responses prior UV-B irradiation on PR activity, cells were cultured in the dark or under UV-B light. When the cells were cultured in the dark for 3 d prior to UV-C exposure, PR activity decreased. When the cells were cultured under UV-B light, however, PR activity increased. These results suggest that exposing the cells to UV-B prior to exposure to UV-C induced an adaptive response towards DNA damage caused by UV-C exposure, and this UV-C induced damage was repaired through PR activity.
|
| Volume |
5(5)
|
| Pages |
467-71
|
| Published |
2006-5-1
|
| DOI |
10.1039/b601971d
|
| PMID |
16685323
|
| MeSH |
Adaptation, Physiological
Animals
Cells, Cultured
DNA Damage*
DNA Repair*
Euglena gracilis / chemistry
Euglena gracilis / genetics
Euglena gracilis / radiation effects*
Kinetics
Light
Photochemistry
Pyrimidine Dimers / analysis
Pyrimidine Dimers / metabolism*
Ultraviolet Rays*
|
| IF |
2.408
|
| Times Cited |
8
|
| Resource |
| Algae |
|
