RRC ID 6185
著者 Ito A, Kiyohara T, Kawabe Y, Ijima H, Kamihira M.
タイトル Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells.
ジャーナル J Biosci Bioeng
Abstract An epithelial cell adhesion molecule, E-cadherin was expressed in NIH3T3 fibroblasts, and cell-cell interactions between keratinocytes and fibroblasts, or between hepatocytes and fibroblasts were artificially engineered. When the E-cadherin-expressing NIH3T3 cells were co-cultured with rat hepatocytes, the cell-cell contacts were formed with high frequency, and enhanced albumin secretion was observed.
巻・号 105(6)
ページ 679-82
公開日 2008-6-1
DOI 10.1263/jbb.105.679
PII S1389-1723(08)70129-4
PMID 18640611
MeSH Animals Cadherins / metabolism* Cell Communication / physiology* Cells, Cultured Epithelial Cells / metabolism* Humans Keratinocytes / metabolism* Mice Microscopy, Fluorescence / methods* NIH 3T3 Cells Recombinant Proteins / metabolism
IF 2.366
引用数 11
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY
リソース情報
遺伝子材料 Mouse E-cadherin full length cDNA (RDB01184)