RRC ID |
6185
|
著者 |
Ito A, Kiyohara T, Kawabe Y, Ijima H, Kamihira M.
|
タイトル |
Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells.
|
ジャーナル |
J Biosci Bioeng
|
Abstract |
An epithelial cell adhesion molecule, E-cadherin was expressed in NIH3T3 fibroblasts, and cell-cell interactions between keratinocytes and fibroblasts, or between hepatocytes and fibroblasts were artificially engineered. When the E-cadherin-expressing NIH3T3 cells were co-cultured with rat hepatocytes, the cell-cell contacts were formed with high frequency, and enhanced albumin secretion was observed.
|
巻・号 |
105(6)
|
ページ |
679-82
|
公開日 |
2008-6-1
|
DOI |
10.1263/jbb.105.679
|
PII |
S1389-1723(08)70129-4
|
PMID |
18640611
|
MeSH |
Animals
Cadherins / metabolism*
Cell Communication / physiology*
Cells, Cultured
Epithelial Cells / metabolism*
Humans
Keratinocytes / metabolism*
Mice
Microscopy, Fluorescence / methods*
NIH 3T3 Cells
Recombinant Proteins / metabolism
|
IF |
2.366
|
引用数 |
11
|
WOS 分野
|
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
|
リソース情報 |
遺伝子材料 |
Mouse E-cadherin full length cDNA (RDB01184) |