RRC ID 6185
Author Ito A, Kiyohara T, Kawabe Y, Ijima H, Kamihira M.
Title Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells.
Journal J. Biosci. Bioeng.
Abstract An epithelial cell adhesion molecule, E-cadherin was expressed in NIH3T3 fibroblasts, and cell-cell interactions between keratinocytes and fibroblasts, or between hepatocytes and fibroblasts were artificially engineered. When the E-cadherin-expressing NIH3T3 cells were co-cultured with rat hepatocytes, the cell-cell contacts were formed with high frequency, and enhanced albumin secretion was observed.
Volume 105(6)
Pages 679-82
Published 2008-6
DOI 10.1263/jbb.105.679
PII S1389-1723(08)70129-4
PMID 18640611
MeSH Animals Cadherins / metabolism* Cell Communication / physiology* Cells, Cultured Epithelial Cells / metabolism* Humans Keratinocytes / metabolism* Mice Microscopy, Fluorescence / methods* NIH 3T3 Cells Recombinant Proteins / metabolism
IF 2.015
Times Cited 11
WOS Category FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Resource
DNA material Mouse E-cadherin full length cDNA (RDB01184)