Reference - Detail
| RRC ID | 65196 |
|---|---|
| Author | Zaninello M, Palikaras K, Naon D, Iwata K, Herkenne S, Quintana-Cabrera R, Semenzato M, Grespi F, Ross-Cisneros FN, Carelli V, Sadun AA, Tavernarakis N, Scorrano L. |
| Title | Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy. |
| Journal | Nat Commun |
| Volume | 11(1) |
| Pages | 4029 |
| Published | 2020-8-12 |
| DOI | 10.1038/s41467-020-17821-1 |
| PII | 10.1038/s41467-020-17821-1 |
| PMID | 32788597 |
| PMC | PMC7423926 |
| MeSH | Adenylate Kinase / metabolism Animals Autophagy* / genetics Axons / pathology Caenorhabditis elegans / metabolism Disease Models, Animal Enzyme Activation GTP Phosphohydrolases / genetics Mice, Inbred C57BL Mice, Knockout Mitochondria / metabolism Mitophagy Mutation / genetics Optic Atrophy, Autosomal Dominant / complications* Phosphorylation Retinal Ganglion Cells / pathology Vision Disorders / complications* |
| Resource | |
| C.elegans | tm5755 tm376 |