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Species Resource Title
Drosophila DGRC#206596 , 5520R-3 Gp93 inhibits unfolded protein response-mediated c-Jun N-terminal kinase activation and cell invasion.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis.
Human and Animal Cells HeLa(RCB0007) , 293T(RCB2202) Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2.
Human and Animal Cells HOS(RCB0992) , 293T(RCB2202) , Saos-2(RCB3688) , A549(RCB0098) PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
Human and Animal Cells SK-MEL-28(RCB1930) Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.
DNA material EGFP-hEFA6A (RDB20108) , EGFP-hEFA6B (RDB20109) , EGFP-hEFA6C (RDB20110) EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.
Human and Animal Cells THP-1(RCB1189) The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation.
C.elegans tm4525 Proteasome activity contributes to pro-survival response upon mild mitochondrial stress in Caenorhabditis elegans.
C.elegans tm6369 Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans.
Human and Animal Cells HS-Sch-2(RCB2230) , HS-PSS(RCB2362) , YST-1(RCB2136) Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors.
Human and Animal Cells RGM1(RCB0876) Mitochondrial cytochrome c release and caspase-3-like protease activation during indomethacin-induced apoptosis in rat gastric mucosal cells.
Human and Animal Cells ROS-17/2.8-5(RCB0462) Rapid activation of MAP kinase by estrogen in the bone cell line.
Human and Animal Cells 293(RCB1637) Analysis of E1A domains involved in the enhancement of CDK2 activity.
Arabidopsis / Cultured plant cells, genes pst08738 , pst12055 Ex vivo processing for maturation of Arabidopsis KDEL-tailed cysteine endopeptidase 2 (AtCEP2) pro-enzyme and its storage in endoplasmic reticulum derived organelles.
Human and Animal Cells MKN28(RCB1000) Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation.
Human and Animal Cells HeLa Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα.
Human and Animal Cells BeWo(RCB1644) , MCF7(RCB1904) , COS-1(RCB0143) Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population.
Human and Animal Cells PC-12(RCB0009) Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
Human and Animal Cells KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
Human and Animal Cells HL60(RCB0041) RGD peptide-induced apoptosis in human leukemia HL-60 cells requires caspase-3 activation.