Reference - Detail
| RRC ID | 65371 |
|---|---|
| Author | Pérez-Jiménez MM, Monje-Moreno JM, Brokate-Llanos AM, Venegas-Calerón M, Sánchez-García A, Sansigre P, Valladares A, Esteban-García S, Suárez-Pereira I, Vitorica J, Ríos JJ, Artal-Sanz M, Carrión ÁM, Muñoz MJ. |
| Title | Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases. |
| Journal | Nat Commun |
| Volume | 12(1) |
| Pages | 49 |
| Published | 2021-1-4 |
| DOI | 10.1038/s41467-020-20269-y |
| PII | 10.1038/s41467-020-20269-y |
| PMID | 33397961 |
| PMC | PMC7782729 |
| MeSH | Alzheimer Disease / enzymology* Alzheimer Disease / pathology* Animals Caenorhabditis elegans / enzymology* Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / metabolism* Disease Models, Animal Epistasis, Genetic Gonads / metabolism Longevity* Mice Phenotype Sensory Receptor Cells / metabolism Steroids / metabolism Steryl-Sulfatase / metabolism* Sulfatases / metabolism* |
| Resource | |
| C.elegans | tm6179 tm1452 tm1011 |