論文 - 詳細
| RRC ID | 65593 |
|---|---|
| 著者 | Kuroda T, Mizutani Y, Cançado CRX, Podlesnik CA. |
| タイトル | Reversal learning and resurgence of operant behavior in zebrafish (Danio rerio). |
| ジャーナル | Behav Processes |
| Abstract |
Zebrafish are used extensively as vertebrate animal models in biomedical research for having such features as a fully sequenced genome and transparent embryo. Yet, operant-conditioning studies with this species are scarce. The present study investigated reversal learning and resurgence of operant behavior in zebrafish. A target response (approaching a sensor) was reinforced in Phase 1. In Phase 2, the target response was extinguished while reinforcing an alternative response (approaching a different sensor). In Phase 3, extinction was in effect for the target and alternative responses. Reversal learning was demonstrated when responding tracked contingency changes between Phases 1 and 2. Moreover, resurgence occurred in 10 of 13 fish in Phase 3: Target response rates increased transiently and exceeded rates of an unreinforced control response. The present study provides the first evidence with zebrafish supporting reversal learning between discrete operant responses and a laboratory model of relapse. These findings open the possibility to assessing genetic influences of operant behavior generally and in models of relapse (e.g., resurgence, renewal, reinstatement). |
| 巻・号 | 142 |
| ページ | 79-83 |
| 公開日 | 2017-9-1 |
| DOI | 10.1016/j.beproc.2017.06.004 |
| PII | S0376-6357(17)30186-9 |
| PMID | 28633953 |
| MeSH | Animals Conditioning, Operant* Extinction, Psychological Models, Animal Reinforcement, Psychology Reversal Learning* Zebrafish* |
| IF | 1.846 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ゼブラフィッシュ | RIKEN WT |