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論文 - 詳細

RRC ID 65994
著者 Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C. M. Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada
タイトル Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds
ジャーナル Journal of Medicinal Chemistry
巻・号 58
ページ 9510-9521
公開日 2015-12-24
DOI 10.1021/acs.jmedchem.5b00792
PMID 26613420
MeSH Adamantane / analogs & derivatives* Adamantane / chemistry* Adamantane / pharmacology Calcitriol / analogs & derivatives* Calcitriol / chemistry Calcitriol / pharmacology Cell Line, Tumor Crystallography, X-Ray Drug Partial Agonism HEK293 Cells Humans Molecular Structure Organ Specificity Receptors, Calcitriol / agonists Receptors, Calcitriol / antagonists & inhibitors Receptors, Calcitriol / metabolism Stereoisomerism Structure-Activity Relationship Transcriptional Activation
IF 6.205
リソース情報
ヒト・動物細胞 THP-1(RCB1189) U937 293(RCB1637) MG-63(RCB1890)