論文 - 詳細
| RRC ID | 76063 |
|---|---|
| 著者 | Snoznik C, Medvedeva V, Mojsilovic-Petrovic J, Rudich P, Oosten J, Kalb RG, Lamitina T. |
| タイトル | The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity. |
| ジャーナル | Proc Natl Acad Sci U S A |
| 巻・号 | 118(40) |
| 公開日 | 2021-10-5 |
| DOI | 10.1073/pnas.2104664118 |
| PII | 2104664118 |
| PMID | 34593637 |
| PMC | PMC8501779 |
| MeSH | Amyotrophic Lateral Sclerosis / metabolism Animals C9orf72 Protein / metabolism* Caenorhabditis elegans / metabolism Cell Nucleus / metabolism* Cells, Cultured DNA Repeat Expansion / physiology Dipeptides / metabolism* Frontotemporal Dementia / metabolism Ligases / metabolism* Motor Neurons / metabolism Nuclear Proteins / metabolism* Rats Repressor Proteins / metabolism* Spinal Cord / metabolism Ubiquitin / metabolism* |
| リソース情報 | |
| 線虫 | tm1380 |