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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Amyotrophic Lateral Sclerosis / metabolism)
生物種 リソース名 タイトル
線虫 tm1380 The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity.
遺伝子材料 pMAMtracker-Luc (RDB19895) , pMAMtracker-Green (RDB19896) Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis.
ショウジョウバエ 4887R-3 , 4901R-3 , 4901R-4 , 5013R-2 , 5013R-3 , 6013R-2 , 7069R-1 , 7069R-2 , 7470R-2 , 7470R-3 , ... ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
ゼブラフィッシュ Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS.
ショウジョウバエ Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
ショウジョウバエ Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.
ショウジョウバエ TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
線虫 tm7084 The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival.
ショウジョウバエ Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration.
ショウジョウバエ RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
ショウジョウバエ 6459R-1,6459R-7 Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
遺伝子材料 GFP-OPTN-WT (RDB16707) , GFP-OPTN-E50K (RDB16708) , GFP-OPTN-E478G (RDB16709) Determination of cytoplasmic optineurin foci sizes using image correlation spectroscopy.
ヒト・動物細胞 201B7(HPS0063) , HPS0251 , HPS0252 , HPS0292 A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
線虫 tm1 , tm4439 FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
ショウジョウバエ 4179R-4 Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
線虫 tm1411 , tm1441 The secreted MSP domain of C. elegans VAPB homolog VPR-1 patterns the adult striated muscle mitochondrial reticulum via SMN-1.
ゼブラフィッシュ Tg(CM-isl1:GFP) Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development.
遺伝子材料 Genome Network Project Human cDNA IRAL001I24 (HGY080616) FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
ショウジョウバエ 9553R-3 Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
線虫 tm4439 Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life span.