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論文 - 詳細
RRC ID
76104
著者
Zeng WY, Tan L, Han C, Zheng ZY, Wu GS, Luo HR, Li SL.
タイトル
Trigonelline Extends the Lifespan of
C. Elegans
and Delays the Progression of Age-Related Diseases by Activating AMPK, DAF-16, and HSF-1.
ジャーナル
Oxid Med Cell Longev
巻・号
2021
ページ
7656834
公開日
2021-1-1
DOI
10.1155/2021/7656834
PMID
34616504
PMC
PMC8487828
MeSH
AMP-Activated Protein Kinases / metabolism*
Aging / drug effects*
Alkaloids / administration & dosage*
Animals
Animals, Genetically Modified
Caenorhabditis elegans / drug effects*
Caenorhabditis elegans / metabolism*
Caenorhabditis elegans Proteins / genetics
Caenorhabditis elegans Proteins / metabolism*
Disease Models, Animal
Forkhead Transcription Factors / genetics
Forkhead Transcription Factors / metabolism*
Heat-Shock Response / drug effects
Kaplan-Meier Estimate
Longevity / drug effects*
Neurodegenerative Diseases / prevention & control*
Oxidative Stress / drug effects
Plant Extracts / administration & dosage*
Signal Transduction / drug effects*
Transcription Factors / genetics
Transcription Factors / metabolism*
Trigonella / chemistry*
Up-Regulation / drug effects
Up-Regulation / genetics
リソース情報
線虫
tm1011