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  • Search Condition : Filter (MeSH = Up-Regulation / drug effects)
Species Resource Title
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (REB04393) Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1β production in microglial cells following activation of β-adrenergic receptors.
Human and Animal Cells SK-N-SH(RCB0426) Cytokines and neurotrophic factors fail to affect Nogo-A mRNA expression in differentiated human neurones: implications for inflammation-related axonal regeneration in the central nervous system.
Human and Animal Cells PC-12(RCB0009) Ca(2+) influx through P2X receptors induces actin cytoskeleton reorganization by the formation of cofilin rods in neurites.
Human and Animal Cells EoL-1 cell(RCB0641) p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
C.elegans tm1011 Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age-Related Diseases by Activating AMPK, DAF-16, and HSF-1.
Human and Animal Cells HeLa Inhibition of HSF1 and SAFB Granule Formation Enhances Apoptosis Induced by Heat Stress.
Human and Animal Cells KG-1-C(RCB0270) Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells.
Human and Animal Cells F-36P(RCB0775) Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce cell cycle progression through the synthesis of c-Myc protein by internal ribosome entry site-mediated translation via phosphatidylinositol 3-kinase pathway in human factor-dependent leukemic cells.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells HeLa Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.
Human and Animal Cells NUGC-4(RCB1939) Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer.
Human and Animal Cells HCE-T(RCB2280) Up-regulation of ZO-1 expression and barrier function in cultured human corneal epithelial cells by substance P.
Human and Animal Cells 293T(RCB22020) β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.
Human and Animal Cells U-937 DE-4(RCB0435) Prostaglandins up-regulate vascular endothelial growth factor production through distinct pathways in differentiated U937 cells.
Pathogenic eukaryotic microorganisms Candida neoformans IFM 40215, Candida parapsilosis IFM 40218, Candida glabrata IFM 40217, Candida albicans IFM 40213 Mariannamides A and B, new cyclic octapeptides isolated from Mariannaea elegans NBRC102301.
Human and Animal Cells TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation.
Human and Animal Cells MKN74(RCB1002) , Kato III(RCB2088) Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase.
Human and Animal Cells JHOM-1(RCB1676) , JHOM-2B(RCB1682) Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary.
Human and Animal Cells T24(RCB0431) Apoptosis of bladder cancer by sodium butyrate and cisplatin.
Human and Animal Cells PC-12(RCB0009) Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways.